Location of superoxide anion in the human colonic mucosa.
نویسندگان
چکیده
منابع مشابه
Location of superoxide anion generation in human colonic mucosa obtained by biopsy.
To identify which cells generate superoxide, inflamed human mucosa was tested with nitro-blue tetrazolium as a probe, because it is reduced by strong reducing agents to form insoluble blue formazan, which then precipitates in tissues. Biopsy specimens from control subjects and patients with ulcerative colitis were studied. The specimens were organ cultured with bubbling air or nitrogen, and inh...
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Perfusion of the colon with ricinoleic acid produces fluid and electrolyte accumulation. The mechanism of these changes in water and electrolyte movement is uknown. These studies were designed to determine whether ricinoleic acid effects active ion transport across isolated rat colonic mucosa. 0.5 mM Na ricinoleate produced significant increases in potential difference (3.8 +/- 0.5 mV) and shor...
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ژورنال
عنوان ژورنال: Gut
سال: 1994
ISSN: 0017-5749
DOI: 10.1136/gut.35.2.284-c